Biotin labeled nucleic acids are molecular probes tagged with biotin, a vitamin that plays a crucial role in various biochemical processes. These biotinylated nucleic acids, whether DNA or RNA, are widely utilized in molecular biology for applications such as hybridization assays, detection, and purification. The high affinity between biotin and streptavidin or avidin allows for the selective isolation of nucleic acids from complex mixtures, enhancing the sensitivity and specificity of analyses. This labeling technique is instrumental in various fields, including genomics, proteomics, and diagnostics, enabling researchers to study gene expression, perform sequencing, and develop targeted therapeutics with greater precision and efficiency. The versatility and reliability of biotin labeled nucleic acids make them invaluable tools in the research and clinical laboratories.